Treat moving cities as the day's main activity
A train's scheduled duration is only one part of moving between hotels. The complete day includes packing, checkout, local travel, station arrival requirements, the train, arrival procedures, another local journey and check-in. If those pieces are absent, an itinerary may suggest that you have an almost full sightseeing day in both cities. That impression disappears as soon as luggage and real addresses enter the plan.
Choose whether the transfer day should protect a relaxed departure or an early arrival. Both can be reasonable, but they lead to different bookings. Do not decide by train duration alone. Compare the total route between your two accommodation addresses and note which parts are fixed, which depend on transport service and which you can adjust yourself.